10 Best Flea Treatments For Dogs 2025 in the UK

FRONTLINE Plus Flea & Tick Treatment for Large Dogs is designed to address the common concerns of pet owners dealing with fleas and ticks. A significant strength of this product is its dual-action formula that not only kills fleas and ticks but also prevents flea eggs from hatching, reducing the chance of future infestations. The active ingredient, Fipronil, is well-regarded for its efficacy and safety, making it a trusted choice among veterinarians.

Ease of application is another highlight, as the liquid form in pipette allows for straightforward usage: simply apply the content at the base of your dog’s neck. This simplicity can be particularly appealing to owners of large dogs, as the product covers dogs weighing between 20-40 kg and is suitable for puppies as young as 8 weeks old.

The treatment's effectiveness lasts up to 4 weeks, which aligns well with the recommended practice of monthly applications to maintain year-round protection. This 6-pack offers 6 months of coverage, providing a cost-effective solution for ongoing flea and tick control. FRONTLINE Plus is a solid choice for large dog owners seeking a reliable and easy-to-use flea and tick treatment, albeit with some delivery limitations.

The Advantage Spot On Flea Treatment for extra large dogs between 25-40kg is a convenient solution for managing flea infestations. The treatment comes in the form of drops, with each pack containing 4 pipettes. It is easy to apply directly to your dog's skin. One of its main strengths is its effectiveness, with imidacloprid as the active ingredient, which works quickly to eliminate fleas and prevents further infestation for up to four weeks.

This makes it a suitable option for large breed dogs of all life stages. The treatment needs to be repeated every four weeks, which is a straightforward routine for ongoing flea prevention. However, one drawback is that it requires monthly reapplication, which might be less convenient for some users compared to longer-lasting treatments. Also, the product is specifically for extra large dogs, so it may not be suitable for smaller breeds or those outside the specified weight range.

For dog owners looking for an effective and easy-to-apply flea treatment for their large breed dogs, the Advantage Spot On Flea Treatment could be a reliable choice.